Selank

Selank is a synthetic peptide derived from tuftsin, a naturally occurring tetrapeptide associated with immunoglobulin G (IgG). It was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences and has been approved as a pharmaceutical in Russia since 2009. Selank extends tuftsin's sequence with additional amino acids (Pro-Gly-Pro) to improve stability and biological activity.

Published research on Selank has focused on anxiolytic (anti-anxiety) and immunomodulatory effects. Studies in the Russian pharmacological literature have compared its anxiolytic activity to that of benzodiazepines, but without the sedation, cognitive impairment, or dependence potential associated with that drug class. A study published in BMC Neuroscience reported that Selank influenced GABA receptor expression in research models. Immune function studies have explored its effects on cytokine production and T-cell activity.

Semax and Selank were developed at the same Russian institute but target different systems. Semax is an ACTH analog that primarily affects cognitive function through BDNF and dopaminergic pathways. Selank is a tuftsin analog that primarily targets anxiety and immune function through GABAergic and immunomodulatory pathways. In simple terms: Semax is studied for focus and cognition, Selank for anxiety and immune regulation. Some researchers use both compounds together for complementary effects.

Published research has consistently noted that Selank produces anxiolytic effects without sedation, motor impairment, or dependence formation in animal models. This distinguishes it from classical benzodiazepines in preclinical comparisons. A 2017 study in BMC Neuroscience confirmed that Selank modulates GABA receptor subunit expression without producing the tolerance patterns seen with diazepam.

Store lyophilized Selank at -20C for long-term stability. Reconstituted vials should be refrigerated at 2-8C and used within 30 days. Protect from direct light and avoid freeze-thaw cycles.

Every batch undergoes third-party HPLC and mass spectrometry testing. HPLC confirms purity (99%+ standard). Mass spectrometry confirms molecular identity. A batch-specific Certificate of Analysis is provided with every purchase and available for download directly on this page.

All Kern products ship same-day (orders placed before 1pm EST). Lyophilized peptides are shipped at ambient temperature and are stable during transit. Upon receipt, store at -20C for long-term stability or 2-8C for near-term use. If the product arrives damaged, contact us within 7 days with photos for a free replacement.

Price differences usually reflect differences in purity, testing standards, and manufacturing quality. Low-cost vendors may skip mass spectrometry verification (which confirms you actually have the right molecule), use lower-grade raw materials, or skip sterility and endotoxin testing. Kern tests every batch with both HPLC and mass spec, and our CoAs are available before you buy.